Which of the following describes LD50 Dermal?

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Multiple Choice

Which of the following describes LD50 Dermal?

LD50 Dermal measures the amount of a substance that, when applied to the skin, would be expected to kill 50% of exposed animals. In this test, the substance is placed on bare skin and observed for mortality; the dose at which half of the subjects die defines the dermal LD50. The described scenario—substance applied to bare skin of an albino rabbit for 24 hours with about half of the test subjects dying—fits this definition exactly. Other options describe different routes or concepts (oral LD50, inhalation LC50, or a non-standard “maximum non-lethal dose”), so they do not describe LD50 dermal.

LD50 Dermal measures the amount of a substance that, when applied to the skin, would be expected to kill 50% of exposed animals. In this test, the substance is placed on bare skin and observed for mortality; the dose at which half of the subjects die defines the dermal LD50. The described scenario—substance applied to bare skin of an albino rabbit for 24 hours with about half of the test subjects dying—fits this definition exactly. Other options describe different routes or concepts (oral LD50, inhalation LC50, or a non-standard “maximum non-lethal dose”), so they do not describe LD50 dermal.

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