Biological substances of Category B must follow which packing instruction?

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Biological substances, Category B (UN 3373) are kept safe for transport by using a specific triple-packaging approach defined in the packing instruction for this category. Packing Instruction 650 sets the requirements: an inner primary container that is leakproof and securely sealed, a secondary packaging that is also leakproof, and enough absorbent material between the layers to contain any spill. This assembly is placed inside a rigid outer packaging with cushioning to withstand normal transport handling. Proper labeling is part of the process too, marking the package as a Biological Substance, Category B with UN 3373. This combination protects handlers, the public, and the environment from exposure in the event of breakage or leakage. Other packing instructions exist for different hazards and higher-risk categories, so they are not applicable to Category B.